Rayna Jaymes and Juliette Barnes face personal and professional challenges as they navigate their paths as artists and individuals. Surrounding them, and often complicating their lives, are their family, friends and, in some cases, lovers, as well as the up-and-coming performers and songwriters trying to get ahead in the business. In Nashville, musicians and songwriters are at the heart of the storm driven by their own ambitions. Some are fueled by their creativity and passion for fame. Others struggle to cope with the pressures of success and are doing everything in their power to stay on top.
In the premiere episode, "Pilot," Rayna learns that her record label wants her to tour as the opening act for newcomer Juliette Barnes, and when she refuses, the stage is set for the ultimate power struggle for popularity. Complicating matters, Lamar's drive for power results in backing Teddy in a run for Mayor of Nashville, against Rayna's wishes.